It was indicated that the antilysozyme activity of enterobacteria is part of the general mechanism of lysozyme resistance of microorganisms and is determined by the presence of ivyC and pliC genes, which encode the lysozyme inhibitors to be secreted. A relationship was established between the high level of antilysozyme activity and the presence of pliC gene of chromosomal or extrachromosomal (plasmid) localization, identified in pathogenic and potentially pathogenic enterobacteria (Institute for Cellular and Intracellular Symbiosis of the Urals Department of RAS).
It was for the first time that representative epizootological evidence was obtained for the existence of active natural foci of tularemia in island ecosystems of extremely high latitudes of the Arctic. Therefore, the groups arriving in the Arctic for the development of the Arctic shelf and the start of the large-scale "cleaning" of its territory should be considered as risk groups for tularemia (FSBI N. F. Gamaleya National Research Center of Epidemiology and Microbiology under the Health Ministry of Russia).